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Instead, it provides slow, steady benefits over time

NAD + intermediates: the biology and therapeutic potential of NMN and NR

Akhter MS, Barabutis N

The observation that higher plasma concentrations of 2 can be achieved after oral delivery than for PZQ, coupled with the greater ex vivo potency of compound 2 , strongly suggest that further optimization will yield an orally bioavailable schistosomicidal agent that will be transformative in the clinical setting

Proc Natl Acad Sci USA 89 : 69836987 Oscarsson J et al

Convenience-driven shortcutsconcurrent dosing, reversing the sequence, compressing the window to 2 hoursreduce efficacy predictably