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A recent meta-analysis of RCTs reported improvements in several metabolic parameters, including markers of glycemic control, insulin sensitivity, and lipid metabolism, demonstrating that targeted modulation of the gut ecosystem can shift clinically relevant endpoints in humans (140)

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Semaglutide is a GLP-1 receptor agonist, while tirzepatide targets both GLP-1 and GIP receptors, which may provide additional appetite control and metabolic support depending on the patient

In addition, inositol participates in the action of serotonin, a neurotransmitter known to control mood and appetite

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