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This information helps your provider decide whether to maintain the current dose or begin dose escalation at the next scheduled adjustment

With that in mind, if you do decide to try not just GLP-1 supplements but any supplement, it's best to consult a health care professional first, Reierson says, "especially when it comes to those claiming to offer significant health benefits." If you buy something through a link in this article, we may earn commission.

HR=Hazard ratio, CI=Confidence interval, CV=Cardiovascular

Incretins are hormones that decrease blood glucose levels

For women specifically, the GIP and glucagon components in retatrutide appear to drive superior fat mass reduction compared to amylin-based combinations, based on available data

Retatrutide distinguishes itself by targeting visceral fat, not just weight