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Recent studies showed that oxidative injuries were involved in neurodegeneration such as Alzheimers and Parkinsons disease [53,54], cancer [55,56], diabetes [57], and cardiovascular diseases [58,59]

Human pharmacokinetics of high dose oral curcumin and its effect on heme oxygenase-1 expression in healthy male subjects

Infiltrating immune cells contribute to a feed-forward loop of inflammation and oxidative stress ( 3.2 Alzheimers disease AD is a neurodegenerative condition with gradual onset and progressive impairment of behavioral and cognitive functions

In addition, several studies have shown that administration of synthetic gut hormones in rodents affects their locomotor activity 27,29