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When people with diabetes were given the glutathione precursors cysteine and glycine, their levels of glutathione went up, and their oxidative stress went down, suggesting that GSH supplementation may be very beneficial in preventing type 2 diabetes-related oxidative stress and tissue damage

Pook M, Tuschen-Caffier B, Kubek J, Schill W, Krause W

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thus, further research should assess the durability of treatment responses and the potential for adverse effects on testicular tissue

The effort needed to optimize these regimens can be experienced as aversive, promote frustration, and generate a desire to avoid such effort, aligning with a region of the brain called the anterior midcingulate cortex, as described by Lisa Feldman Barrett and colleagues