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The effect of tirzepatide on 24-hour mean systolic BP, diastolic BP, and heart rate (HR) measured during 24-hour ambulatory BP monitoring (ABPM) in individuals living with obesity without T2DM, has been evaluated in the SURMOUNT-1 ABPM sub-study.34 After 36 weeks of treatment, tirzepatide was associated with statistically significant and clinically meaningful reductions in the mean 24-hour systolic BP at all doses and reduced diastolic BP at the 2 lower doses.34 Simultaneously, tirzepatide treatment was associated with a dose-dependent increase in the mean 24-hour HR.34 Fortunately, there is no clear evidence that tirzepatide increases the risk of atrial fibrillation.35 5
Women and adults aged 66 to 75 saw the most significant decrease in obesity
With compounded tirzepatide, some prescribers modify this protocol
Many patients with commercial insurance pay a copay
STATs Anil Oza spoke with nine current and former NIH officials as well as five outside researchers, who described the often demoralizing and ambiguous process
