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If constipation becomes bothersome, gentle stool softeners or increased water intake usually provide relief

While the U.S faced a shortage of semaglutide in 2024 and early 2025, pharmacies could legally produce bulk compounded versions of the drug because shortages trigger temporary allowances under federal law to fulfill patient demand

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It also presents a comparative analysis of the differences in cancer risk between GLP-1RAs and other antidiabetic medications

However, because so much of the drug is still wasted during digestion, a single daily pill must contain a massive dose just to match the power of a tiny weekly shot

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