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Treated animals demonstrated a 2.6-fold reduction in tumor incidence, accompanied by a 22.6% decrease in chromosomal abnormalities within bone marrow cells, suggesting potential protective cellular effects

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Dehydration is one of the most common causes of fatigue, dizziness, and headaches on these drugs, and it is also one of the easiest to overlook because thirst signals can be blunted

Indeed endocannabinoid signaling through CB1R regulates the activity of dopamine (DA) neurons in the VTA [52], which projects to the nucleus accumbens, a key brain reward region activated by addictive drugs including THC [53, 54]

Apr 2024;33(2):e13990

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