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The release of cytochrome c activates a proteolytic cascade that culminates in apoptotic cell death (Navarro & Boveris, 2009)

doi: 10.3389/fnmol.2025.1549366 Received 21 December 2024 Accepted 12 March 2025 Published 07 April 2025 Volume 18 - 2025 Edited by Inigo Ruiz de Azua, Johannes Gutenberg University Mainz, Germany Reviewed by Beatrice Ferrari, San Matteo Hospital Foundation (IRCCS), Italy Ken-ichiro Nakajima, Nagoya University, Japan Keisuke Ito, University of Shizuoka, Japan Updates Copyright 2025 Shiimura, Kojima and Sato

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Combined use of the two drug classes may enhance clinical outcomes in DKD

According to him, clinicians assess biochemical markers and imaging before initiating therapy to ensure safe and effective outcomes