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Constipation is the most persistent side effect, affecting roughly 15 to 20 percent of long-term users, and often responds to increased fiber intake and hydration

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Results of the present experiment showed that nutritional value of the spinach decreased through increased levels of Zn and K in feeding solution as they cause to less accumulation of micronutrients such as Fe, Cu, Mn, Mg as well as Ca although chlorophyll content and the yield of spinach increased