A closed conformational state of IRAP is created that is believed to be induced upon ligand binding
This process, known as demyelination, results in nerve cell damage
Van Mierlo LD, Meiland FJ, Van Hout HP, Droes RM
The total scores on the BPRS and the CGI-S scores decreased, not significantly, at one, two, and three months from baseline
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T1-weighted images were obtained using a Rapid Imaging with Refocused Echoes (RARE) pulse sequence with varying TIs (Pre-contrast: 280, 500, 900, 1200, 1500, 4650, 1200 ms