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We reasoned that as the GluC cleavage specificity is different from the three catalytic activities of the proteasome, considering that the proteasome caspase-like site cleaves more efficiently after aspartic acid residues than glutamic acid (Kisselev et al, 2003), we could distinguish proteasome-generated peptides from those produced by GluC

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Zn is a crucial trace element recognized as an insulin mimic that promotes adipogenesis and glucose uptake by isolated adipocytes in a manner similar to that of insulin

Normal levels of GSH have been shown to have roles in restricting serine availability to preserve regulatory T cell (Treg) functionality ( Monocytes and macrophages are also influenced by GSH levels