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Summary: The half-life of retatrutide is approximately 6 days, based on pharmacokinetic data from Phase 1 and Phase 2 clinical studies, which supports its once-weekly subcutaneous injection regimen

Figure 2 2.2.1 Type I cells Also known as glial cells, they comprise 50% of the total population of TBC

Positive effects in IBD and colitis models

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Somasundaram S, Sigthorsson G, Simpson RJ et al (2000) Uncoupling of intestinal mitochondrial oxidative phosphorylation and inhibition of cyclooxygenase are required for the development of NSAID-enteropathy in the rat