The number of days on which analgesics were required was significantly reduced with Pycnogenol from 2.1 to 1.3 days and changed less in the placebo group, from 1.9 to 1.7 days
No significant heterogeneity was found among RCTs in the diabetic subgroup (I 2 = 0%, P = 0.38), and thus fix-effects model was chosen
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