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J Clin Oncol (2017) 35(15_suppl):9536

It is well documented that patients with neurofibromatosis type 1 (NF1) have a greater lifetime risk of developing MPNSTs (813%) and worse prognosis in comparison with sporadic cases, with 5-year disease-specific survival of 1638% versus 4257%, respectively [2, 5,6,7,8,9,10]

doi: 10.1177/1545968310397706

If the phenotypes of the mutants can be successfully restored to wild type, this will confirm that only the correct genes have been deleted and further validate the specific phenotypes ascribed to each GDH mutant

These chemicals commonly found in firefighting foam (AFFF), nonstick cookware, and industrial waste do not break down naturally and have been linked to cancer, reproductive issues, and other serious health conditions

Clinical-criteria denials turn on whether the chart supports the criteria as written