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All protocols were conducted and approved in the accordance to the LIH Animal Welfare Structure guidelines

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Pyroptosis A form of programmed cell death triggered by infection or cellular stress that is, unlike apoptosis, characterized by inflammation as it involves the activation of inflammasomes and caspase-1, leading to cell swelling, membrane rupture and the release of pro-inflammatory cytokines such as interleukin-1 (IL-1) and IL-18

Metastasis, the spread of cancer cells from the primary tumor to distant sites, is a hallmark of cancer and a major cause of cancer-related mortality [117]

336 In addition, miR-145 regulates the expression of the drug resistance gene MDR1, thereby improving drug sensitivity to 5-aminosalicylic acid and glucocorticoids in the treatment of UC

Regulation of Hemolytic Anthrolysin O by Extracellular Proteases of Bacillus anthracis