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The double-blind trial randomized 27,564 patients with stable #ASCVD to either placebo or subcutaneous evolocumab (either 140 mg every 2 weeks or 420 mg once monthly) for a median follow-up period of 2.2 years

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serendipitously discovered that GLP-1(736) exerts potent antinociceptive effects in the formalin test, prompting a systematic investigation of its role in alleviating pain hypersensitivity and its underlying mechanisms [24]

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