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This provides some empirical evidence into the mechanism of action of these treatments beyond theoretical considerations

But some bodybuilders supplement with IGF-1 in hopes of gaining more strength (7, 9)

Mathiesen DS, Lund A, Holst JJ, Knop FK, Lutz TA, Bagger JI

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Pain scores (measured by WOMAC) improved by up to 75.8%, with more than one in eight participants becoming completely pain-free by the end of the trial