Una vez que vence la patente, otros fabricantes pueden producir biosimilares (equivalentes a los genricos, pero para biolgicos), lo cual reduce los precios significativamente
References Cai M, Choi T, Xie Y, Al-Aly Z
Why choose between SGLT2 inhibitors and GLP1-RA when you can use both?: the time to act is now
Oral vs injectable GLP-1: does delivery method change the timeline The GLP-1 space is expanding beyond weekly injections
Higher drug levels mean stronger insulin secretion in response to meals, which could theoretically cause hypoglycemia
Several studies found that GLP-1RAs might have direct effects on adipogenesis, lipotoxicity, fatty acid oxidation, cytokines related to hepatitis and fibrosis, and intestinal microbiota (193, 195)