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Beyond Weight Loss: Metabolic Improvements Participants also saw improvements in cardiometabolic health markers: Blood pressure: Systolic BP decreased by 7.4 mmHg Triglycerides: Fell by 30% HDL cholesterol: Increased by 8% (the "good" cholesterol) Liver fat: Reduced by 50% based on imaging studies HbA1c: Decreased by 0.4% even in participants without diabetes Visceral fat: Reduced by 42% (more than total weight loss percentage) Some of these improvements (particularly the visceral and liver fat reductions) are larger than the overall weight loss, which points to direct metabolic effects from the glucagon receptor activation

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Ein weiteres Prparat, CagriSema (GLP-1 + Amylin) , befindet sich aktuell in der klinischen Phase-3-Prfung

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By integrating liposomal encapsulation with velocity-driven techniques, researchers can attain higher control over drug release, improved localisation at target areas, and increased bioavailability, rendering this strategy a potent platform for non-invasive and efficient transdermal therapies