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Based on the presentation of symptoms, Rome criteria further categorize primary chronic constipation into functional constipation (FC) and constipation-predominant irritable bowel syndrome (IBS-C) [5]

3,094 non-diabetic, obese men ages 1850 who received a prescription of semaglutide were identified and subsequently matched to an equal number cohort of non-diabetic, obese men who never received a prescription of semaglutide

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It may further reduce appetite by decreasing plasma ghrelin levels (91, 92)

Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation

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