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10.1001/jama.2020.16909 29 BjorkliC.SandvigA.SandvigI
(2005) Phospholipase D activity is essential for actin localization and actin-based motility in Dictyostelium
Its main active ingredient, total dajizin triterpenes, reduces the expression of ACSL4 in the rat model of RA, increases the expression of glutathione and GPX4, and upregulates Kelch-like ECH-associated protein 1 and HO-1 in the Nrf2/HO-1/GPX4 pathway, indicating that total dajizin triterpenes can inhibit cell aberrant ferroptosis by suppressing lipid peroxidation and thus exert therapeutic anti-RA effects [168]
Phospholipid vesicles are biocompatible (consisting of the same components as our body's cell membranes) and small enough to penetrate the walls of blood vessels
For patients dealing with photodamage or hyperpigmentation, GHK-Cu reduces both by addressing the oxidative stress and inflammatory processes that drive them