Dependence on exercise L-Carnitine requires exercise to produce its fat-loss effect, because without active fat oxidation there is no substrate for it to transport
Think of it as taking a naturally occurring signaling molecule and engineering a version that specifically targets brain receptors rather than peripheral tissues
The cold-chain logistics for peptide storage and distribution also add cost
And in the aftermath of the FDA's announcements first, last fall with tirzepatide and then quite recently with semaglutide, the patients I've spoken with have been really concerned about that and not sure what they'll do
Targeted exercise can reduce fat in some areas, though spot reduction through exercise alone is limited
Platelet-Rich Plasma (PRP): The patient's own blood is drawn, processed to isolate platelets and plasma, and then re-injected into the face to stimulate collagen production and improve skin quality/tightness