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We recently reviewed elsewhere the vast array of therapeutic opportunities that the targeting of each one of these receptors offers, not only as a hope for the future, but as a current success, as several MC drugs have already been approved and many others are in clinical phase of development (135)

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These pathways help cells adapt and respond to whatever life throws at them.* Alpha Lipoic Acid Alpha lipoic acid (ALA) is one of the most powerful antioxidants

Skin changes and temperature dysregulation leading to loss of turgor, dryness and therefore itching and surface breaks are common in cirrhosis and the use of moisturizers to improve hydration and maintain barrier integrity is always the first step toward reducing pruritus (4)

However, it will not go away completely

It only protects against UVB and not UVA rays (the 320-400 nm range) so always choose products that contain other sunscreens too