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While safety data is encouraging, with no significant differences in adverse events compared to placebo, a larger Phase IV outcomes trial is ongoing to confirm the long-term cardiovascular benefits of enlicitide, and Merck has initiated the FDA approval process, with the drug in the fast track program

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(NYSE: ABBV) announced positive topline results from a phase 1 multiple ascending dose study evaluating ABBV-295, its long-acting amylin analog being developed for obesity and metabolic disease treatment

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However, studies have shown that glutathione is largely broken down during the digestive process, meaning that much of the beneficial properties are lost