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GLP-1 is able to stimulate cAMP formation in RIN 1046-38 cells, which in turn causes an increase in insulin mRNA levels and insulin release, and insulin accumulation in the culture fluid was observed by adding GLP-1 (7-37) to RIN 1046-38 cells for 1 h incubation (Drucker et al., 1987)
doi: 10.3389/fddsv.2026.1792418 Received 20 January 2026 Revised 11 March 2026 Accepted 16 March 2026 Published 10 April 2026 Volume 6 - 2026 Edited by Liang Xu, University of Kansas, United States Reviewed by Christel Menet, Confo Therapeutics, Belgium Anukriti Saran, Banasthali University, India Updates Copyright 2026 Niazi
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