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Proinflammatory cytokines further stimulate ROS overproduction aggravating ARDS and lung damage causing a vicious circle between oxidative stress and cytokine storm

Challenges and limitations of medical obesity treatment remain GLP-1s generally require lifelong use to maintain results

For secondary outcomes, the BMI % difference from baseline in the monotherapy group was -3.88% vs

Insufficient GSH, the only antioxidant in the hypothalamus, may cause ferroptosis in some neurons, leading to further metabolic disorders

J Physiol (2004) 555(Pt 1):23140.10.1113/jphysiol.2003.051722 219 HeinemeierKMBjerrumSSSchjerlingPKjaerM

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