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Adverse effects include severe nausea, severe vomiting and severe hypoglycemia (low blood sugar levels)

The other thing worth sitting with observational data of this size and quality, with each patient serving as their own control, is closer to causal evidence than people give it credit for

GH naturally declines beginning in the late 20s and accelerates after 40

Chronic excess can produce an iatrogenic acromegaly phenotype progressive soft-tissue and bone changes in hands, feet and face and contribute to hypertension and cardiac strain

Cardiovascular outcomes studies in people with T2D and high cardiovascular risk have shown that DPP4i have an overall cardio-neutral profile 32,33,34,35,36,37 , while GLP1-RAs were associated with decreased all-cause mortality and major adverse cardiovascular events (MACE) 38

Practice good hygiene: Taking daily baths and frequently changing your underwear and clothes can help reduce the strong urine smell