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10.1002/cpt1971122part2360 Clin Pharmacol Ther

The differences are small but worth understanding

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This mechanistic distinction is critical for evaluating their efficacy

FOXO4-DRI is a breakthrough "third-generation" senolytic peptide engineered to selectively eliminate senescent cells ("zombie cells") that accumulate with aging

In other words, the 1 in 10 people getting worse after starting with the B12 shots may just be the result of one of the other coexisting illnesses getting worse