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Semaglutide works by mimicking the action of a hormone called GLP-1 (glucagon-like peptide-1)

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These people may need direct supplementation with methylcobalamin or adenosylcobalamin rather than cyanocobalamin

Furthermore, liraglutide and semaglutide have both demonstrated anti-fibrotic effects and their use in preclinical models prevents NASH-driven HCC progression (Sanyal et al., 2025

GLP-1 agonists like Wegovy, Ozempic, and Mounjaro, which are used to treat type 2 diabetes and obesity, have been growing in popularity so much so that in December 2025, the Food and Drug Administration (FDA) approved an oral pill form of Wegovy for weight loss