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In focus: Semaglutide and GLP-1 Patent Filings This momentum followed earlier milestones in the companys insulin portfolio, including FDA approvals for Tresiba and Ryzodeg in 2015 and expanded use of Tresiba in children by 2016

These compounds are sold for research, not as approved prescription therapy, and the long-term maintenance picture after stopping mirrors what we see with every appetite agent

Lane, J

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The Frias 2023 Phase 2 in T2D showed cagrilintide+semaglutide produced a -2.2 percentage-point HbA1c reduction at 32 weeks versus -1.8 for semaglutide alone