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The drug works by mimicking the effects of GLP-1 and hitting receptors for another hormone, GIP, which leads to even more weight loss
Glycemic mechanism and insulin sparing sensitization not secretion: fasting insulin and C-peptide fall while insulin sensitivity (HOMA2-%S) rises +31.8/+43.2/+49.9% (SURPASS J-mono, Hamamoto 2025)
The gaps in evaluation were striking: This does not mean telehealth is inherently unsafe
Mechanism of Action Phentermine: Stimulates the brain to suppress appetite GLP-1 injections: Mimic natural hormones that control hunger and fullness This is the biggest difference
Heres a quick term glossary
Liddelow, S
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![PDF] Switching Between Glucagon-Like Peptide-1 Receptor Agonists: Rationale and Practical Guidance](https://figures.semanticscholar.org/69d84ad0979bcded8fc643f42a28ce77fbc5b3ff/3-Table2-1.png)
