Investigational endoscopic therapy maintains weight after GLP-1 discontinuation by Doug Brunk The treatment could provide an "off-ramp for patients who either can't or don't want to be on these drugs long-term." Late-night eating, stress tied to bowel issues by Doug Brunk Meal timing might magnify the impact of stress on the microbiome via the gut-brain axis." Emulsifiers found to lower gut metabolites, not inflammation by Doug Brunk "These results point towards a beneficial influence of an emulsifier-free diet and possibly detrimental impact of specific emulsifiers on the gut-microbe interaction." Colectomy risk high after ulcerative colitis hospitalization by Julie Greenbaum Given the high rates of colectomy within one year, this appears to be an important target for quality improvement in the care of patients with ulcerative colitis. FIB-4 plus M2MPGi may boost fibrosis detection by Doug Brunk Two-step biomarker strategy improves accuracy while reducing unnecessary referrals in MASLD

Berberine may affect blood glucose levels and could potentially interact with antidiabetic medications, increasing the risk of hypoglycaemia
Injection data: Wilding JPH, et al
Both can work wellit depends on your comfort and how your body responds
The local GLP-1 system in the olfactory bulb is required for odor-evoked cephalic phase of insulin release in mice
J Biol Chem 285(1):793804 Olivetti G, Abbi R, Quaini F, Kajstura J, Cheng W, Nitahara JA, Quaini E, Di Loreto C, Beltrami CA, Krajewski S, Reed JC (1997) Apoptosis in the failing human heart