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The FDAs formal guidance against compounded semaglutide projected to eliminate USD 3.6 billion in compounding pharmacy and telehealth revenue in 20252026 creates disruption risk for approximately 1.5 million patients receiving compounded GLP-1 outside branded channels

Most published data comes from in vitro and animal studies suggesting collagen synthesis and wound healing potential

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Annals of the New York Academy of Sciences 1194:27-33

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Many compounded batches were found to originate from unregistered or uninspected overseas facilities