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Similar effects are often seen after bariatric surgery, Mounjaro, Wegovy, or even lifestyle changes that lead to sudden weight loss

Published data (STEP 4 trial, JAMA 2022) show that most patients regain a portion of lost weight after discontinuation

Obestatin binds to GRP 39, a receptor of the same subfamily than ghrelin receptor, to decrease food intake and body weight in an opposite manner to ghrelin (Stengel et al., 2009

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Pregnant or breastfeeding women should consult their physician before use