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A meta-analysis that reported findings from seven randomized controlled trials indicated that vitamin D supplementation may improve blood vessel function in individuals with CKD, and this vitamin may be more effective during the earlier stage of CKD and when high doses are consumed

If you are not very B12 deficient or not experiencing fatigue or nerve sensations as one of your symptoms, you may not notice the benefits until after youve had 2-3 injections over several weeks

Chambers, D

Vitamin C is water-soluble and generally absorbs well, but taking too much at once can cause digestive upset

Very good treatment

The strongest FDA warning issued, a black box warning also explains how the reactions may be worse in certain groups of people, such as women who are pregnant, pediatric patients, and elderly patients