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Epigenetic reprogramming of melanoma cells by vitamin C treatment

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A randomized controlled trial on the effect of metformin in CHD patients without diabetes showed that it (2000 mg/day, P.O for 12 months) not only decreased oxidative stress but also lowered left ventricular mass (LVM) and improved blood pressure [227]

PMID: 19652057

Implementing DMT1 inhibitors as an intervention strategy demonstrates significant therapeutic potential (Jing et al., 2020)