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Common adverse effects include gastrointestinal symptoms, which affect the majority of patients to varying degrees: Nausea (20-44% of patients) usually most pronounced during dose escalation Diarrhea (20-30%) Constipation (15-24%) Vomiting (9-24%) Abdominal pain (6-10%) These symptoms typically diminish over time as physiological adaptation occurs

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V.Barrientos-PerezM.FainbergU.Frimer-LarsenH.HafezM.HaleP

and reconstituting the thermoreversible gel formulation with sterile water prior to administration

Because of these dosing complexities, having personalized guidance is essential

Strukturalnie czsteczka to acuch 39 aminokwasw z acylacj wic albumin, o masie ~4813,5 g/mol