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The TMAO-generating enzyme FMO3 reduced RCT, decreased the intestinal absorption of cholesterol, and changed the composition and size of the bile acid pool (Warrier et al., 2015

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SHBG varies widely among women Total testosterone includes SHBG-bound testosterone (which is inactive) and free testosterone and albumin-bound testosterone

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Microcirculation dysfunction Studies have shown that NAPQI-induced microvascular congestion in the centrilobular region precedes direct hepatocyte injury

Reduced fast food and sugar/ junk food