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However, an RCT on 35 patients with migraine, showed that supplementation with N-acetylcysteine (1,200 mg), vitamin E (500 IU), and vitamin C (1,000 mg) daily for 3 months resulted in lower frequency, severity, and duration of headaches and lower acute medication use (90)

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Takeaway Injectable L-carnitine is generally considered more effective than oral supplementation due to its higher bioavailability and more direct absorption into the bloodstream

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