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Currently, this technology has been extensively researched for the delivery of vaccines and therapeutics and has been applied in the treatment of various diseases [173]
Hwang C, Sinskey AJ, Lodish HT (1992) Oxidized redox state of glutathione in the endoplasmic-reticulum
Following the exclusion of reports with incomplete methodologies, 93 studies were ultimately selected for comprehensive analysis
ChaC1, as a tumor-influencing factor, enhances ER stress, contributing to necroptosis and ferroptosis of multiple cancers, including metastatic melanoma (64), breast (54), prostate (65) and primary liver cancer (66), Burkitt's Lymphoma (67), head and neck squamous cell carcinoma (68), glioblastoma multiforme (GBM) (69), oral squamous cell carcinoma, T lymphoblastic leukemia Molt4 cells and colitis-associated carcinogenesis (15)
What I found especially noteworthy is that the reduction appeared stronger for venous thromboembolic events than for some arterial cardiovascular outcomes such as myocardial infarction