Biotransformation can temporarily increase reactivity
Semaglutide has a half-life of approximately one week, which means that after missing a single dose, you still have significant levels of the drug in your system
J Am Heart Assoc 2016;5:e003046.ArticlePubMedPMC 43
So each time they use the pen, it gives them the dose thats required. However, many GLP-1 users have noticed that after their four expected doses, theres still medication in their injection pen, providing them with possibly a fifth dose, or whats been coined the golden dose by GLP-1 users
doi: 10.1016/j.celrep.2020.107768 47 GutzwillerJ-PHruzPHuberARHamelCZehnderCDreweJet al
You shouldnt take semaglutide if: You or a close family member has ever had medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2)