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Its interaction with the enzyme results in JNK activation and c-Jun phophorilation 106
As of February 18, 2026, the class has expanded with established agents like semaglutide, liraglutide, dulaglutide, and exenatide, alongside dual GLP-1/GIP agonists such as tirzepatide, which are often discussed in GLP-1 contexts due to overlapping mechanisms and indications
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Catalysis of the oxidative folding of ribonuclease A by protein disulfide isomerase: dependence of the rate on the composition of the redox buffer
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