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Frontiers in medicine

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Oct 15 2021;22(20)doi:10.3390/ijms222011156 Campos R, Garrido A, Guerra R, et al

Why a Blend Outperforms Single-Component Research Setups Investigators studying a single pathway in a complex tissue-repair model face a fundamental limitation: the biology of tissue recovery involves simultaneous vascular, cellular, and inflammatory processes

4.4 Activation of the reninangiotensin-aldosterone system and disturbances in calciumphosphate homeostasis Aberrant activation of the RAAS is a critical driver of CKD progression, contributing to glomerular hypertension, inflammation, and fibrosis