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Description

Based on identifying pockets in the GLP-1 receptor, as determined by Cryo-EM, chemists synthesized a number of molecules, one of which, orforglipron, did trigger activity

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GLP-1/GLP-1r Signaling in Regulation of Adipocyte Differentiation and Lipogenesis

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Kalra S

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Wharton S, Davies M, Dicker D, et al

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