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S., Olsen, C

Abrupt discontinuation can trigger rebound hunger and rapid weight regain

GLP-1 supplements, often prescription drugs, are used to treat diabetes and obesity by enhancing the hormone's activity

On the research side, whether boosting GLP-1 over the long term (beyond 12 months) is safe for cats and dogs is still a mystery

Discussion While GLP-1 RAs are powerful anti-obesity medications (AOMs), they do raise some serious concerns most notably, up to 40% of the profound weight loss induced by these agents can be due to loss of lean mass 3,4,5 and prior studies have shown that a significant portion of this lean mass is muscle 33,34,35

With lifestyle changes, around 60% of people who use Saxenda lose at least 5% of their body weight