It also stimulates the release of dopamine, a neurotransmitter commonly associated with the "pleasure, reward, and motivation" centers of the brain
The main antidiabetic drugs used clinically are thiazolidinediones (e.g., troglitazone, rosiglitazone), metformin, sulphonylureas and glinides (10)
These findings underscore that not only rare pathogenic mutations, but also common variants exert modifying and additive effects on disease trajectories (Chung et al., 2023
Its significance in preserving and enhancing health, from boosting immunity to protecting cells, is why the science behind it is so intriguing and why its therapeutic applications hold such great promise
In the process of physiological ageing, both systemic and tissue-specific systems show functional downfalls, which, when projected to the brain, translate into weakening defence and metabolic strain resulting from age-dependent declines of the cardio-vascular system and overall decreases in metabolism
Trulicity improves patient convenience with its user-friendly autoinjector device (like an EpiPen), the first available for this class of drugs
