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Although GLP-1 RAs have demonstrated efficacy even without structured behavioral support, their broader therapeutic potentialparticularly regarding long-term behavior change, psychological stabilization, and sustained weight lossmay be most effectively realized when embedded within a biopsychosocial framework

Cell-NP interactions can trigger various signaling cascades at the cell surface, leading to different structural changes [74]

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Patients with severe gastroparesis, active gallbladder disease, or diabetic retinopathy requiring active treatment should pursue in-person endocrinology care rather than telehealth

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