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In this study, a carboxy-modified heptamethine cyanine (Cy-7) derivative was chosen as the fluorescence reporter due to its excellent biocompatibility and intrinsic ability to target mitochondria [39], [40], [41]

It suffers from bioavailability issues, and the CNS-targeting theory remains unvalidated for this specific compound

And slice electrophysiology, which extends the original EEG-based observations into a controlled system

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Hypocatalasemia: a new genetic carrier state

Indeed, this study disclosed that the decline of MMSE score in the long term was generally slow (Supplementary Figure S5)