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Dose escalation protocols used in trials were designed to minimise gastrointestinal tolerability issues

Evid-Based Complement Altern Med 2022(1):4024331 Tangjitman K, Wongsawad C, Kamwong K, Sukkho T, Trisonthi C (2015) Ethnomedicinal plants used for digestive system disorders by the Karen of northern Thailand

As the population ages, the global prevalence of OA is escalating

Room temperature (2025C) accelerates this timeline dramatically: ipamorelin loses approximately 1015% potency per week, while tesamorelin can degrade by 2030% within 1014 days

Although this study focused on treating obesity only, the observed effects on eating behaviors highlight the potential for tesofensine to be beneficial in treating eating disorders

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